copper peptides in skin remodeling and scarless skin healing


Repair Your Skin

Diminish Existing Scar Tissue By Activating Normal Skin Remodeling from Inside the Body By Topically Applying Natural Copper Peptides.

Copper Peptides in the Restorative Secretion of Snails Help to Reinforce Skin Remodeling and Minimize Scars.

Improperly healed acne skin lesions may yield aberrant accumulation of collagen and defective skin cell layering.

A type of compounds called “copper peptides” has been developed in the laboratory for their capacity to reorganize the process of injury repairing by minimizing scar development and increasing skin remodeling and they are present naturally in the complex biological ingredient that is fundamental in our BIO SKIN CARE products.

For years, the only source of this compound had been copper peptides synthezised in the laboratory by using soy proteins and thanks to the innovative research of Dr. Loren Pickart. Dr. Pickart is a biochemist who originated this ground-breaking theory that copper peptides have skin healing properties, stimulate and are integral to the cycle of skin renewal (www.skinbiology.com).

What exactly are copper peptides and how can they change the biological response to injuries? Generally speaking, peptides are tiny sections of proteins. (And the proteins are the one of the key construction blocks of most living cells, the other are complex carbohydrates or sugar chains and DNA.) Certain types of peptides have a huge affinity for copper, to which they bind very tightly. The final compound made of a peptide and a copper atom has become known as a copper peptide.

The secretions collected from snails provide the only biological source of these molecules as they have glycosaminoglycans (GAGs) that tightly bind divalent copper cations Cu +2 and peptides, copper peptides.

Dr Pickart discovered copper peptides while doing experiments that intended to reverse certain effects of aging in animals. Since then, GHK-Cu and certain other copper-peptides, have been found to accelerate the regeneration and repair process of many kinds of mammalian tissues.

Studies, at numerous universities and research centers, have found that copper-peptides:

- Accelerate injury repair (humans, mice, rats, guinea pigs, pigs, dogs)

- Increase skin re-epithelialization (humans, animals)

- Elevate skin graft transplant success (pigs)

- Elevate hair transplant success (humans)

- GHK analogs with fatty residue analogs enlarge hair follicle size, stimulate hair growth and reduce hair loss (humans, mice, rats). Increases hair growth after chemotherapy (rats)

- Reverse aging effects on skin (humans)

- Thickens skin, shrinks small and large wrinkles, fades blotchiness and blemishes, improves elasticity, and elevates keratinocyte and fibroblast generation, reinforces the subcutaneous fat layer

- Stimulate bone repairing (guinea pigs, pigs, rabbits)

- Cure stomach ulcers (rats)

- Cure injured intestinal linings (humans, rats)

- Block oxidative damage in tissues.

- Return normal function in livers damaged by toxins (rats)

- Numerous anti-inflammatory actions (reduces liberation of oxidizing iron, TNF-alpha, TGF-beta-1, IL-1)

Several substances can have a beneficial effect on wound repairing. A particular feature of copper peptides is that they reduce scar tissue generation while promoting normal skin remodeling. In other words, they help restore the damaged area to its original state.

The process of copper peptide action is somewhat complex. Copper bound to aminoacids activates the degradation of "extra-large" collagen aggregates found in scars and induces the synthesis of smaller more regular collagen found in normal skin. It also induces the synthesis of elastin, proteoglycans, glycosaminoglycans, and other components of the skin matrix. Other important effects of Copper Peptides involve the ability to regulate the growth rate and distribution of different kinds of cells; important anti-inflammatory action; and the ability to prevent the liberation of oxidation-promoting iron into the tissues. The net result is a faster, better and "cleaner" resolution of wounds.

Can copper peptides be useful for normal skin protection and renewal?

While the production and breakdown of collagen, elastin, and water-holding GAGs are in a continuous balance in young healthy skin, after age 25 the skin's production of collagen, elastin, and the water-holding GAGs is reduced while the frequency of breakdown of these factors is raised and starts wrinkle development and loss of elasticity. The problem becomes progressively more accentuated with passing years. The good news is there are now synthetic (synthetic copper peptides) and biological substances (snail glycoconjugates that also contain copper peptides as part of a intricate biological activator of skin repair and remodeling) that can counteract this process.

The available evidence showed the following possible skin benefits of copper peptides:

Several existing skin care solutions are based on the idea of eliminating the outermost or even deeper layers of skin. The resulting healing process activates skin remodeling, resulting in smoother, younger looking skin. Since copper peptides improve healing and improve skin remodeling, they can increase the effect of treatments based on several forms of controlled skin damage. In particular, copper peptides can be useful after several forms of laser resurfacing, dermabrasion, and chemical peels.

Copper peptides are effective against several forms of skin irritation, mainly due to their anti-inflammatory properties. Skin irritation, even in the absence of open injuries, dramatically accelerates skin aging by stimulating the formation of free radicals and other toxic undesirable products. Some common skin rejuvenation solutions, such as tretinoin (Retin A, Renova) and alpha hydroxy acids can cause irritation. If during treatment you suffer skin irritation for an extended period of time, your skin will possibly end up in worse shape than when you started. In many cases, copper peptides can reduce or avoid the irritation and help maximize treatment benefits.

It is always easier to prevent the damage than to fix it later. To a significant degree, skin aging is induced by the accumulation of minor day-to-day damage from sun, detergents, wind, acne, abrasions and so forth. As these tiny lesions heal, they form microscopic imperfections, which eventually accumulate to become visible signs of aging. While it remains to be further investigated, it seems that copper peptides can help diminish the damage from daily wear and tear of the skin. For instance, one investigation found that copper peptides helped recover skin integrity after exposure to SLS, a common detergent found in many shampoos, cleansers, and dishwashing/laundry products.

Can copper peptides reverse wrinkles and other signs of aging in healthy skin?

Yes, because copper peptides stimulate the reduction of unusually large cross-linked collagen (the one present in scars and, in a minor degree, in wrinkles). They also stimulate the production of "normal" collagen found in normal skin. In one small investigation, copper peptides stimulated collagen production in healthy skin. In fact, in that investigation, copper peptides induced a stronger stimulation of collagen synthesis than tretinoin (Retin A, Renova) or ascorbate (vitamin C). While clinical studies have shown the positive effects on photo-aged skin from the daily application for 4 to 8 weeks of cosmetic solutions with the snail secretions, which contain copper peptides and complex glycoconjugates.

While standard use of synthetic copper peptides stimulates collagen synthesis and has antioxidant effect (by triggering the antioxidant enzyme superoxide dismutase), exaggerated use of synthetic copper peptides taken from soy proteins can have an opposite effect by raising the levels of free copper. Free copper promotes free radical damage and collagen breakdown, inducing premature skin aging. These troubles do not seem to appear among the major part of copper peptide users. However, there are occasional reports showing that such side-effects might appear with overuse or, rarely, even normal use in certain individuals. Ideally, a sufficiently extensive investigation is needed to better quantify these risks.

Finally, copper peptides found as part of the intricate glycoconjugates created by land snails are a safe and effective skin treatment. Their potential to improve the repairing of several kinds of skin lesions is well established. And the snail secretions decelerate the development of the signs of skin aging by restricting the consequences of daily wear and tear. Also, the snail secretions have an effect on skin renewal due to the presence in them of enzymes that degrade damaged proteins into their amino-acid components and trigger an harmonic reconstructing and remodeling of the skin tissues.

What makes the copper peptides in BIOSKINCARE efficient and reliable?

A biological cosmetic solution, not a drug or pharmaceutical product.

BIOSKINCARE™ is made with the organic secretions from a land snail (Helix Aspersa Muller), the same they produce to quickly restore their own skin and shell when damaged. It is a viscose liquid that is converted into an odorless white cream.

Study of the mucin has shown that it contains activators of skin growth factors, glycoproteins, natural anti-inflammatory and immune modulating proteins, antimicrobial peptides, glycosaminoglycans that tightly bind divalent copper cations Cu +2, and acharan sulfate glycosaminoglycan (GAGs) as a protein-free polysaccharide.

Unlike harsh chemicals and physical processing often used to create protein supplements, which unfortunately denatures (destroys) the biological structure of proteins yielding something that is not fully absorbed and utilized by the human body. The proteic secretions of the snail are taken as they are originally to make them into our product, without any process that may change their composition and on the contrary their bio-availabity for living cells is completely preserved.

Double blind experiments comparing placebo to the active ingredient on one side of the face compared to the other using impartial procedures to measure wrinkle depth have demonstrated improvement in this parameter as well as skin smoothness, suppleness, and reduction of hiperpigmentation in more than 80% of subjects studied. Most people have seen improvements in as little as two weeks when they have used BIOSKINCARE™ cream twice a day every day.

Topical application of BIOSKINCARE™ is also a potent message that signals to your body that it is being taking care of in a balanced and proper manner, with all the ingredients that help it accelerate the natural skin healing process.

Use of the product night and day for a period of 2 months ensures: Decrease in wrinkles depth, Increase in collagen and elastin from within the deep layers of the skin, giving skin firmness, Optimization of the water holding ability of healthy skin, reducing sagging and fragility, Decrease of age spots, dark pigmentation, hyperpigmentation, melasma, Reduction of topic dermatitis, Restoration of the natural skin color of those affected by hiperpigmentation in people of all skin colors, including African, Asian & Latin.

BIOSKINCARE™ helps your skin repair and moisturize itself! There is nothing like it! It has been used on age lines, boils, diaper rash, abrasions, skin ulcers, infected nails, chilblains, age spots, acne, athlete's foot, diabetic sores, skin allergies, insect bites/stings and stretch marks and other skin problems and conditions. It is just excellent. Wounds heal with minimal scar formation. Use BIOSKINCARE™ and help your skin rejuvenate naturally!

BIOSKINCARE™ has a two fold effect: (1) Reduces debris, injuries, anomalous and necrotic tissues & cleanses the skin as it helps to dissolve all damaged structures into their amino-acid and other components by the action of enzymes. (2) Facilitates tissue restoration.

It leaves your skin smooth, soft, refreshed and with use over a period of time it shrinks contractures and takes away keloid, hypertrophic and all types of scars and blemishes: acne, the effects on the skin of radiotherapy for cancer, keratosis bumps, dryness, razor nicks and burns, cuts, scrapes, eczema, roughness, dermatitis, actinic keratosis lesions, scars, blisters, and the list can go on and on... It clears and enhances the complexion.

Bioskincare

Made in the USA. 50 grams = 1.76 oz


Regular Price for One Bottle: $69.98

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Natural Acne Gel, Rosacea Remedy & Scar Healing BIOSKINCLEAR

This gel is oil free and a natural remedy for acne, rosacea, and scar healing with moisturizing seaweed extracts. Best for people with very oily skin conditions.

BIOSKINCLEAR

BIOSKINCLEAR Benefits

Made in the USA. One Month's supply 50 grams = 1.76 oz

50 Grams in One Airless Pump Bottle: $59

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All our products are safe for children, moms-to-be and breast fedding mothers.



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BIOCUTIS Skin Treatment Products

Life is inseparably connected with water, because water is the origin of all life. It is the initial, intermediate and final product of countless reactions in the living organism. Water serves as a solvent, a means of transportation, a means of colling and of storing heat in our largest human organ – the skin!

Beautiful and healthy skin is dependent on a good reliable supply of water. Dry skin is often the sign of a lack of vitally important nutrients and active agents. Dry skin lacks lustre and quickly leads to small, visible lines. Fluid from inside and supplementary body care from outside can protect, care for and maintain the skin.

With increasing age, the elasticity of the skin diminishes and body care becomes even more important. The skin becomes thinner and less resistant. The whole regeneration process runs more slowly and deficits become visible. Therefore the skin is reliant on a complete and sophisticated supply of trace elements, mineral salts and sufficient moisture and moisture-retaining substances.

In order to cope with this situation a little creature that merries around with its skin exposed nude under the sun, very much like us humans do with our face and neck and other parts of our body, has created the most complete active "solution" that extensively moisturises the skin, protects it from free radicals, repairs the skin whenever damaged, triggers its healthy renewal, and when applied to human skin does the same for it, enabeling it to show up, become and remain healthy, soft and smooth.

BIOSKINMOISTURIZER™BIOSKINMOISTURIZER
Biological Skin Moisturizing. A new biological skin moisturizing cream that embodies (a) natural enzymes that dissolve damaged tissues and dying and dead cells; (b) skin renewal activators that speed keratinocyte turnover, promote the proliferation of fibroblasts that give rise to new collagen, elastin and the proteoglycans and glycosaminoglycans thereby hastening the resolution of skin damage and averting inflamm-aging or chronic inflammation caused by accumulated sun damage, and (c) antimicrobial peptides that keep growing bacteria on check and help resolve mild and moderate skin infections. 50 grams (1.76 oz) $69.98.

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BIOSKINBALM™BIOSKINBALM
Relieves eczema, dermatitis, psoriasis scales, skin rashes, rosacea, dry skin, and a wide variety of very dry skin conditions. This product is a 100% natural, nourishing and healing, super soothing, hydrating, biological skin treatment balm which has been specifically designed to leave your skin feeling balanced, deeply hydrated and velvety soft. In addition to the previous properties, it is also suited for the routine care of sensitive skin prone to allergies. This balm is also excellent as a night-time recovery treatment cream. Furthermore it contains powerful antioxidants that inhibit free radical production and provide both cellular and DNA protection from UV damage. 50 gram (1.76 oz) jar = $75.98

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BIOSKINLOTION™BIOSKINLOTION
To keep the body hydrated.Similar to BIOSKINCARE and BIOSKINMOISTURIZING. It contains a mix of antioxidants, cell-communicating ingredients, and intercellular substances, as those are the ingredients that help skin keep a normal level of hydration, build collagen and prevent cellular damage. 4 oz pump bottle: $59.95

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BIOSKINCARE™BIOSKINCARE
This is the first product we made and our bestseller. It has the same ingredients as in BIOSKINMOISTURIZER in a proportion that is best suited for combination and oily skin. 50 gram jar = $69.98.

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BIO STRETCH MARK CREAMBIO BODY CREAM for Stretch Marks
To prevent pregnancy stretch marks, strengthen fragile skin, firm sagging breasts and body areas and reduce cellulite. It also works for newly formed stretch marks and scars, while BIOSKINEXFOL works best for old, rough and raised marks. This is similar to the cream in BIOSKINCARE, in a more economical container, with 4 oz. but for use only on the body, not on the face, because it contains a higher concentration of our natural biological complex which results in an invisible film that retains in moisture by occluding the area where it is applied but may feel a little tacky on the face. 4 oz (120g) tottle = $79.98

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BIO SKIN REJUVENATIONBIO SKIN REJUVENATION
Same cream base and enzymes as in BIOSKINCARE to "digest"; or dissolve blemishes, speed skin turnover and tighten skin, and an added ingredient: human growth factor peptide, derived from the melanocyte-stimulating-hormone. Blocks melanin synthesis, and reduces the formation of unwanted pigmentation, allowing control over skin tone and brown spots. Leaves skin bright and refreshed! 50 gram jar = $79.

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ACNE, ROSACEA ™ SCARS - CLEAR SKINBIOSKINCLEAR
Oil free moisturizing gel for acne, rosacea and facial scars. The product is based on a natural substance secreted by a little animal to function as its powerful immune modulator and skin regeneration trigger. Removes dead cells, unclogs sebum canals and dissolves scar tissues by enzymatic hydrolysis, without peeling. Promotes the proliferation of antimicrobials that control acne bacteria. Boosts reproduction of glycosaminoglycans, the molecules that retain water, thus truly moisturizing the skin from within. Tells the body it is being taken care off and can moderate an otherwise extreme inflammatory reaction that may end up destroying healthy skin cells together with bacteria and sebum that has turned into a foreign matter. 50 gram (1.76 oz) airless pump bottle $59.

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BIOSKINEXFOLBIOSKINEXFOL
A home microdermabrasion cream with the same high quality micro-crystals professionals use to breakdown hard, rough and old scar tissues, and allow for a deeper penetration of our exclusive all natural skin moisturizing and regeneration complex contained in the microdermarasion cream.120 gram (4 oz) jar = $89

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