Acne starts during puberty when your body activates your sebum glands to produce an oily substance that when on the surface of the skin it lubricates it and shields your skin from infection by pathogens that thrive there permanently. If sebum does not outflow swiftly through the sebum canals to the surface it produces multiple skin injuries that initiate an inflammatory reaction and the sebum trapped there becomes a rich feeding ground for the proliferation of bacteria.

The skin is confronted with heavy demands when one of these infections occur. Areas with continued acne infections caused by severe or moderate acne frequently develop deficiencies of essential ingredients, impairing the skin's ability to defend itself and heal efficiently.

Acne infections damage collagen and elastin fibers, sever the microvascular network and damage and kill cells. When healing happens, usually after a long time if an adequate acne treatment has not be applied, a scar is left in the skin. The healthy functional tissue (skin) is replaced by connective tissue (scar).

Natural Ingredient Helps Heal Acne

Bacteria have survived for millions of years by developing resistance to new stressors including natural antibiotics like penicillin. What simply occurs is that the bacteria, with a high rate of mutation, ends up changing one or more of its enzymes that are used to break the link between a target protein and the antibiotic. As a result, the antibiotic does not have effect.

But this system fails when the attacker punches holes in the cell membrane, as peptide antibiotics do. To defend itself, the bacterium would have to change the entire composition of the cell membrane. And to change the composition of a membrane would mean changing many of the enzymes that are responsible for making the complex membrane in the first place.

Peptide antibiotics respond within minutes helping treat acne instantly. Part of the reason for this rapid response is how the peptide acts on the cell membrane. But to kill a cell, the peptide must also quickly locate the bacterial membrane. How does this happen? The answer lies in the structure of the cell membrane.

The plasma wall of eukaryotic cells is much different than the wall of a prokaryotic cell. Eukaryotic cell walls are constructed of a phospholipid bilayer and cholesterol. In consequence, these walls have a low negative electrical charge. On the other hand, a bacterial wall is composed by fats and sugars. This difference in construction means that bacteria have a high negative electrical charge that promptly attracts the peptide antibiotics.

Peptide antibiotics are effective. In one clinical trial for the treatment of meningitis, a sickness that affects 3,000 children a year, a peptide antibiotic not only killed the bacterium which mades the toxin, but it also bound to the toxin avoiding the damage the endotoxin produces. But bringing a new drug to clinical trial is time consuming and expensive. It takes $300 million to bring a drug to market. This price covers every thing from discovery, identification, synthesis and clinical trials. This process can also take ten or more years to accomplish.